The artificial dermis Integra, Johnson & Johnson Medical, Norderstedt, Germany is widely used in the treatment of excessive burn injuries. It is also used in reconstructive surgery when large soft-tissue defects could not be covered with local or free flaps.

In this article a 25-year old patient who presented with an early childhood burn of the trunk and lower extremity was treated with Integra((R)) in combination with the vacuum assisted closure (V.A.C.((R)), KCI, Texas, U.S.A.) and split thickness skin grafting. The combination of the artifical dermal substitute with negative pressure therapy has lead to a complete healing of Integra((R)) and the skin graft.

During the whole treatment sterile wound conditions were present and time-consuming dressing changes could be prevented. Hospital stay was shortened because the patient could be treated as an outpatient with an ambulant vacuum assisted closure device.


The use of the artificial dermis (Integra((R))) in combination with vacuum assisted closure for reconstruction of an extensive burn scar - A case report.
J Plast Reconstr Aesthet Surg. 2009 Jun 10; Leffler M, Horch RE, Dragu A, Bach AD (Hubmed.org)